Time in Therapeutic Range

How it works

Comparisons

Evidence quality

Highlighted claims

• Time in therapeutic range (TTR) is the standard metric of anticoagulation quality. — Evaluation of a pharmacist-led patient-self-testing model for warfarin management in patients undergoing mechanical heart valve replacement in China: a multicentre, open-label, randomised, controlled trial
• TTR is calculated using Rosendaal's linear interpolation method applied to all INR values collected. — Evaluation of a pharmacist-led patient-self-testing model for warfarin management in patients undergoing mechanical heart valve replacement in China: a multicentre, open-label, randomised, controlled trial
• Chinese patients achieve a mean TTR of approximately 55%, substantially below the 60–77% observed in developed nations. — Evaluation of a pharmacist-led patient-self-testing model for warfarin management in patients undergoing mechanical heart valve replacement in China: a multicentre, open-label, randomised, controlled trial
• Higher testing frequency in PST directly drove improved TTR and reduced extreme INR values in both the subtherapeutic and supratherapeutic directions. — Evaluation of a pharmacist-led patient-self-testing model for warfarin management in patients undergoing mechanical heart valve replacement in China: a multicentre, open-label, randomised, controlled trial
• The usual care arm's low TTR of 55.1% combined with a 12-month follow-up and 556 participants gave this trial adequate statistical power to detect adverse event differences. — Evaluation of a pharmacist-led patient-self-testing model for warfarin management in patients undergoing mechanical heart valve replacement in China: a multicentre, open-label, randomised, controlled trial