TP53
Cross-source consensus on TP53 from 1 sources and 5 claims.
1 sources · 5 claims
How it works
Comparisons
Background
Evidence quality
Highlighted claims
- Elephants carry 20 copies of TP53, compared to a single copy in humans. — Animals Resistant to Diseases That Kill Humans
- TP53 is a tumor suppressor gene that detects DNA damage and triggers either cell repair or apoptosis. — Animals Resistant to Diseases That Kill Humans
- Elephants have over 100 times more cells than humans but do not develop cancer at the rate statistics would predict. — Animals Resistant to Diseases That Kill Humans
- TP53 is referred to as the guardian of the genome because of its central role in preventing malignant transformation. — Animals Resistant to Diseases That Kill Humans
- Redundant TP53 copies continue suppressing tumor formation even when some copies are functionally compromised. — Animals Resistant to Diseases That Kill Humans