Translation Initiation
Cross-source consensus on Translation Initiation from 1 sources and 4 claims.
1 sources · 4 claims
How it works
Highlighted claims
- Cells under stress rapidly reduce global translation while preserving or enhancing translation of selected mRNAs needed for survival and repair. — Stress-induced Eukaryotic Translational Regulatory Mechanisms
- Translation initiation is emphasized as the main control point because it determines global translation rate and requires assembly of many macromolecules. — Stress-induced Eukaryotic Translational Regulatory Mechanisms
- Translation is presented as the earliest and most direct gene-regulatory layer affected by cellular stress. — Stress-induced Eukaryotic Translational Regulatory Mechanisms
- Cap-dependent initiation depends on eIF4F binding the 5-prime cap and PABP binding the poly(A) tail. — Stress-induced Eukaryotic Translational Regulatory Mechanisms