Tumor Senescence
Cross-source consensus on Tumor Senescence from 1 sources and 5 claims.
1 sources · 5 claims
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Highlighted claims
- Tumor cells can enter a non-replicative senescent state despite tumor growth often being defined by sustained proliferation. — Senescent Cells in Growing Tumors: Population Dynamics and Cancer Stem Cells
- The central interpretation is that tumor senescence is real but may not restrain long-term tumor growth. — Senescent Cells in Growing Tumors: Population Dynamics and Cancer Stem Cells
- Senescence may be induced by telomere shortening, DNA damage, oxidative stress, or oncogene-associated stress responses. — Senescent Cells in Growing Tumors: Population Dynamics and Cancer Stem Cells
- The hierarchical model allows senescence to remain present in growing cancers if cancer stem cells continue expanding. — Senescent Cells in Growing Tumors: Population Dynamics and Cancer Stem Cells
- Senescence markers have been reported to increase during tumor progression even as tumors keep growing. — Senescent Cells in Growing Tumors: Population Dynamics and Cancer Stem Cells