Vitamin D Receptor Polymorphism

Uses

How it works

Dosage & preparation

Risks & contraindications

Background

Evidence quality

Highlighted claims

• Vitamin D receptor polymorphism makes the receptor structurally less able to respond to vitamin D, reducing the effect of normal doses. — 7 Ways to Boost Your ABSORPTION of Vitamin D
• Genetic testing can reveal whether a person carries the vitamin D receptor polymorphism variant. — 7 Ways to Boost Your ABSORPTION of Vitamin D
• Some individuals carry genetic variants of the vitamin D receptor that reduce its sensitivity to vitamin D. — The Best Remedy for Lungs — Infection, Asthma, and COPD
• Multiple common factors including dark skin pigmentation, obesity, insulin resistance, advancing age, and low sun exposure further reduce the body's ability to obtain or use vitamin D. — The #1 Best Nutrient for Autoimmune Conditions — The Coimbra Protocol
• All or nearly all patients with autoimmune disease have an increased resistance to the effects of vitamin D. — The #1 Best Nutrient for Autoimmune Conditions — The Coimbra Protocol
• The underlying cause of vitamin D resistance in most autoimmune patients is a genetic variant in the vitamin D receptor that reduces its sensitivity to vitamin D. — The #1 Best Nutrient for Autoimmune Conditions — The Coimbra Protocol
• People with this genetic variant may need to increase their maintenance dose to 30,000 IU, as no other intervention can override the genetic barrier. — 7 Ways to Boost Your ABSORPTION of Vitamin D
• VDR polymorphism can be identified through genetic or clinical testing. — The Best Remedy for Lungs — Infection, Asthma, and COPD
• Standard vitamin D supplementation doses of 4,000–6,000 IU/day may produce little to no benefit in people with VDR polymorphism. — The Best Remedy for Lungs — Infection, Asthma, and COPD
• The vitamin D receptor polymorphism can be acquired during life, triggered by severe sustained stress, trauma, grief, or drug exposure — not only through genetic inheritance. — The #1 Best Nutrient for Autoimmune Conditions — The Coimbra Protocol